MeSH definition : A small GPI-linked glycoprotein expressed on the surface of normal and malignant B-CELLS;
T-CELLS; MONOCYTES; MACROPHAGES; NK CELLS; and GRANULOCYTES. It is expressed densely
and without modulation in many malignant T-cell neoplasms and therefore a target for
antibody therapies (e.g., ALEMTUZUMAB).;
A small GPI-linked glycoprotein expressed on the surface of normal and malignant B-CELLS;
T-CELLS; MONOCYTES; MACROPHAGES; NK CELLS; and GRANULOCYTES. It is expressed densely
and without modulation in many malignant T-cell neoplasms and therefore a target for
antibody therapies (e.g., ALEMTUZUMAB).