CAMPATH-1 Antigen

Preferred Label : CAMPATH-1 Antigen;

NCIt synonyms : Cambridge Pathology 1 Antigen; CDW52; CD52 Antigen; CDW52 Antigen; CD52; Epididymal Secretory Protein E5; He5; Human Epididymis-Specific Protein 5;

NCIt definition : CAMPATH-1 antigen (61 aa, 7 kDa) is encoded by the human CD52 gene. This protein may play a role in spermatogenesis and lymphocyte biology.;

NCIt note : Encoded by the CDW52 wt Allele, CDW52 is a glycosylphosphatidylinositol-anchored glycoprotein expressed on the surface of essentially all normal and malignant B and T cells, a majority of monocytes, macrophages and natural killer (NK) cells, a subpopulation of granulocytes, and tissues of the male reproductive system.;

Details

Origin ID

C38908;

UMLS CUI

C0376272;

OMIM relation
- Campath-1 antigen [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CD52 protein, human [MeSH Supplementary Concept]
- CD52 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CD52 Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Alemtuzumab [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune System Process [NCIt concept]
- Spermatogenesis [NCIt concept]
is_target
- Alemtuzumab [NCIt concept]
- Anti-CD52 Monoclonal Antibody ALLO-647 [NCIt concept]
- Campath-1G [NCIt concept]
- Gatralimab [NCIt concept]

Keyword's position in hierarchy(ies) :

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