Nogo Proteins - CISMeF

Preferred Label : Nogo Proteins;

MeSH definition : Myelin proteins that are expressed as three isoforms: Nogo-A, Nogo-B, and Nogo-C. These share a C-terminal reticulon homology domain (RHD), consisting of two hydrophobic membrane domains flanking a 66 amino acid (Nogo-66) hydrophilic region. A long transmembrane region allows conformations that either span the entire membrane or fold into a hairpin conformation. Nogo inhibits NEURITE outgrowth and modulates wiring and the restriction of SYNAPTIC PLASTICITY in the adult central nervous system. It also regulates neurite fasciculation, branching, and extension in the developing nervous system.;

MeSH synonym : Nogo Protein; Reticulon-4 Protein; Reticulon 4 Protein;

DeCS synonym : Neurite Growth Inhibitor 35-350; NI-35 Protein; Nogo-66 Protein; Nogo-A Protein; Nogo-B Protein; Nogo-C Protein;

MeSH hyponym : Nogo C Protein; Neurite Growth Inhibitor 35 350; NI-35-250; NI 35 250; Nogo A Protein; NI-250 Protein; NI 250 Protein; NI-220 Protein; NI 220 Protein; NI 35 Protein; Nogo B Protein; Reticulon 4-B Protein; Reticulon 4 B Protein; Nogo 66 Protein;

Details

Origin ID

D000070798;

UMLS CUI

C0911852;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Reticulon-4 [NCIt concept]
Record concept(s)
- NI-35 protein [MeSH concept]
- Nogo Proteins [MeSH concept]
- Nogo-66 protein [MeSH concept]
- Nogo-A protein [MeSH concept]
- Nogo-B protein [MeSH concept]
- Nogo-C protein [MeSH concept]
- neurite growth inhibitor 35-350 [MeSH concept]
Related MeSH Supplementary Concept(s)
- RTN4 protein, human [MeSH Supplementary Concept]
- Rtn4 protein, Xenopus [MeSH Supplementary Concept]
- Rtn4 protein, mouse [MeSH Supplementary Concept]
- Rtn4 protein, rat [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Atinumab [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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