Atinumab - CISMeF

Preferred Label : Atinumab;

NCIt synonyms : Immunoglobulin G4-Kappa, Anti-[Homo sapiens RTN4 (Reticulon 4, Neurite Outgrowth Inhibitor, NOGO), Isoform A], Homo sapiens Monoclonal Antibody; 6A3-IgG4;

NCIt definition : A monoclonal antibody directed against reticulon-4, with immunomodulating activity. Atinumab binds to reticulon-4, stimulating neurite outgrowth, which may prevent neuronal damage or may facilitate the regeneration of damaged neurons. Reticulon-4, also called Neurite outgrowth inhibitor or Nogo, is an inhibitor of neurite outgrowth and may prevent neuronal regeneration in the central nervous system.;

UNII : 9UBQ62RW32;

CAS number : 1226761-65-4;

Molecule name : ATI355;

Details

Origin ID

C97942;

UMLS CUI

C3273713;

See also inter- (CISMeF)
- Nogo Proteins [MeSH Descriptor]
- RTN4 protein, human [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
chemical_or_drug_affects_gene_product
- Reticulon-4 [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

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