Preferred Label : Thyroid cancer, nonmedullary, 1;
Symbol : NMTC1;
CISMeF acronym : NMTC1;
Type : Phenotype, molecular basis known;
Alternative titles and symbols : Familial nonmedullary thyroid cancer, papillary; PACT; PTC; Papillary carcinoma of thyroid; Nonmedullary thyroid carcinoma, papillary; TPC;
Description : Nonmedullary thyroid cancer (NMTC) comprises thyroid cancers of follicular cell origin
and accounts for more than 95% of all thyroid cancer cases (summary by Vriens et al.,
2009). The remaining cancers originate from parafollicular cells (medullary thyroid
cancer, MTC; 155240). NMTC is classified into 4 groups: papillary, follicular (188470),
Hurthle cell (607464), and anaplastic. Approximately 5% of;
Inheritance : Autosomal dominant;
Molecular basis : Susceptibility conferred by mutation in the NK2 homeobox 1 gene (NKX2-1, 600635.0012);
Neoplasia : Nonmedullary thyroid carcinoma (papillary); Goiter, multinodular;
Prefixed ID : #188550;
Origin ID : 188550;
UMLS CUI : C4721429;
Automatic exact mappings (from CISMeF team)
- factor IX [Blood Transfusion thesaurus concept]
- Broader ORDO disease(s)
- CISMeF manual mappings
- Currated CISMeF NLP mapping
- DO Cross reference
- False automatic mappings
- Genes related to phenotype
- HPO term(s)
- ORDO concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
