INPP5D wt Allele

Preferred Label : INPP5D wt Allele;

NCIt synonyms : SHIP; SH2 Containing Inositol Phosphatase, Isoform B Gene; MGC142142; MGC104855; SIP-145; Signaling Inositol Polyphosphate 5 Phosphatase SIP-145 Gene; SHIP1; MGC142140; Inositol Polyphosphate-5-Phosphatase, 145kDa Gene; hp51CN; SHIP-1; Inositol Polyphosphate-5-Phosphatase, 145-kD Gene; Inositol Polyphosphate-5-Phosphatase D wt Allele; Inositol Polyphosphate-5-Phosphatase, 145kD Gene; p150Ship;

NCIt definition : Human INPP5D wild-type allele is located in the vicinity of 2q37.1 and is approximately 192 kb in length. This allele, which encodes phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 protein, plays a role in the regulation of many signal transduction pathways.;

NCIt note : Expression of the INPP5D gene may suppress B cell tumorigenesis.;

GenBank Accession Number : U57650;

Details

Origin ID

C95112;

UMLS CUI

C2986916;

Currated CISMeF NLP mapping
- Ship (physical object) [SNOMED CT concept]
- ships [MeSH Descriptor]
- ships [MeSH concept]
OMIM relation
- Inositol polyphosphate-5-phosphatase, 145-kd [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 2q37.1 [NCIt concept]
gene_is_element_in_pathway
- B Cell Receptor Signaling Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
gene_plays_role_in_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Phospholipid Metabolism [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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