TRIM21 wt Allele

Preferred Label : TRIM21 wt Allele;

NCIt synonyms : RO52; SSA1; RNF81; Tripartite Motif-Containing 21 wt Allele; SSA; Autoantigen Ro/SSA, 52-kDa Gene; Sicca Syndrome Antigen A Gene; Sjogren Syndrome Antigen A1 (52kDa, Ribonucleoprotein Autoantigen SS-A/Ro) Gene; Sjögren Syndrome Antigen A1 (52kDa, Ribonucleoprotein Autoantigen SS-A/Ro) Gene;

NCIt definition : Human TRIM21 wild-type allele is located in the vicinity of 11p15.5 and is approximately 9 kb in length. This allele, which encodes E3 ubiquitin-protein ligase TRIM21 protein, plays a role in the regulation of both cell cycle progression and ubiquitinylation of proteins. Polymorphism of the gene is associated with systemic lupus erythematosus.;

NCIt note : The TRIM21 gene may be involved in viral infection defense responses.;

GenBank Accession Number : AF391283;

Details

Origin ID

C94753;

UMLS CUI

C2986652;

OMIM relation
- Tripartite motif-containing protein 21 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Systemic Lupus Erythematosus [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 11p15.5 [NCIt concept]
gene_is_element_in_pathway
- Systemic Lupus Erythematosus Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Regulation Process [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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