Pegzerepoetin Alfa

Preferred Label : Pegzerepoetin Alfa;

NCIt synonyms : Methoxy Polyethylene Glycol-Epoetin Beta; Continuous Erythropoietin Receptor Activator;

NCIt related terms : methoxypolyethylene glycol epoetin beta; Ro 50-3821;

NCIt definition : A pegylated form of recombinant human erythropoietin, a glycosylated protein naturally produced in the kidney that stimulates erythrocyte production in the bone marrow. Methoxypolyethylene glycol epoetin beta may reverse anemias induced by cancer therapy. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of anemia in patients who are receiving chemotherapy. It is a form of erythropoietin (a substance produced in the kidneys that stimulates the production of red blood cells) that has been changed in the laboratory.;

UNII : LR3UXN0193;

CAS number : 917756-28-6; 677324-53-7;

Drug name : Mircera;

Molecule name : Ro 50-3821; R744;

Codes from synonyms : CDR0000346492; CDR0000346491;

Details

Origin ID

C87201;

UMLS CUI

C1328071;

Automatic exact mappings (from CISMeF team)
- Continuous erythropoietin receptor activator (disposition) [SNOMED CT concept]
- continuous erythropoietin receptor activator [MeSH concept]
Currated CISMeF NLP mapping
- Methoxy polyethylene glycol-epoetin beta [ICD-11 Extension code]
- Methoxy polyethylene glycol-epoetin beta [SMS substance]
- Methoxy polyethylene glycol-epoetin beta (substance) [SNOMED CT concept]
- methoxy polyethylene glycol-epoetin beta [MeSH concept]
See also inter- (CISMeF)
- Methoxy polyethylene glycol-epoetin beta (product) [Inactive SNOMED CT concept]
- Substance with continuous erythropoietin receptor activator mechanism of action (substance) [SNOMED CT concept]
- continuous erythropoietin receptor activator [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Methoxy polyethylene glycol-epoetin beta (product) [Inactive SNOMED CT concept]
- Methoxy polyethylene glycol-epoetin beta (substance) [SNOMED CT concept]
- Product containing methoxy polyethylene glycol-epoetin beta (medicinal product) [SNOMED CT concept]
- methoxy polyethylene glycol-epoetin beta [ATC Code]
Validated automatic mappings to BTNT
- methoxy polyethylene glycol-epoetin beta [ATC Code]
chemical_or_drug_affects_gene_product
- Erythropoietin Receptor [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Receptor Activation Process [NCIt concept]
chemical_or_drug_has_physiologic_effect
- B-Cell Activation [NCIt concept]
- Hematopoiesis Induction [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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