continuous erythropoietin receptor activator

Preferred Label : continuous erythropoietin receptor activator;

MeSH note : a third-generation erythropoietic molecule created by integrating a large polymer chain into the molecule, thus increasing the molecular weight to twice that of epoetin at approximately 60 kDa; the methoxy-polyethylene glycol polymer chain is integrated via amide bonds between the N-terminal amino group or the e-amino group of lysine (predominantly lysine-52 or lysine-45), using a single succinimidyl butanoic acid linker; an erythropoiesis-stimulating agent for the treatment of anemia;

MeSH synonym : CERA (erythropoietin receptor activator);

Related MeSH term : epoetin beta pegol;

Is substance : O;

Details

Origin ID

C508420;

UMLS CUI

C1701991;

ATC code(s)
- methoxy polyethylene glycol-epoetin beta [ATC Code]
Currated CISMeF NLP mapping
- Methoxy Polyethylene Glycol-Epoetin beta [NCIt concept]
- Methoxy polyethylene glycol-epoetin beta [SMS substance]
- Substance with continuous erythropoietin receptor activator mechanism of action (substance) [SNOMED CT concept]
MeSH term(s) associated for indexing
- erythropoietin [MeSH Descriptor]
- polyethylene glycols [MeSH Descriptor]
Record concept(s)
- continuous erythropoietin receptor activator [MeSH concept]
- methoxy polyethylene glycol-epoetin beta [MeSH concept]
- mircera [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing continuous erythropoietin receptor activator (product) [SNOMED CT concept]
- Substance with continuous erythropoietin receptor activator mechanism of action (substance) [SNOMED CT concept]
Validated automatic mappings to BTNT
- Methoxy polyethylene glycol-epoetin beta (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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