F-Box-Like/WD Repeat-Containing Protein TBL1XR1

Preferred Label : F-Box-Like/WD Repeat-Containing Protein TBL1XR1;

NCIt synonyms : Transducin Beta-Like 1X-Related Protein 1; TBL1-Related Protein 1; Nuclear Receptor Corepressor/HDAC3 Complex Subunit TBLR1; F-Box-Like WD Repeat-Containing Protein TBL1XR1; TBL1XR1; Transducin Beta Like 1 X-Linked Receptor 1;

NCIt definition : F-box-like/WD repeat-containing protein TBL1XR1 (514 aa, 56 kDa) is encoded by the human TBL1XR1 gene. This protein is involved in the modulation of transcription.;

NCIt note : F-box-like/WD repeat-containing protein TBL1XR1 is a component of the N-Cor transcriptional repressor complex, which may recruit the 19S proteasome complex, leading to the proteosomal degradation of N-Cor complex. (UniProt);

Details

Origin ID

C80118;

UMLS CUI

C2700039;

OMIM relation
- Transducin-beta-like 1 receptor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TBL1XR1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- TBL1XR1 Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- F-Box Domain [NCIt concept]
- WD Repeat [NCIt concept]
gene_product_plays_role_in_biological_process
- Proteasome Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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