Padeliporfin - CISMeF

Preferred Label : Padeliporfin;

NCIt synonyms : Palladium-Bacteriochlorophyll Derivative WST11;

NCIt definition : A vascular-acting photosensitizer consisting of a water-soluble, palladium-substituted bacteriochlorophyll derivative with potential antineoplastic activity. Upon administration, paldeliporfin is activated locally when the tumor bed is exposed to low-power laser light; reactive oxygen species (ROS) are formed upon activation and ROS-mediated necrosis may occur at the site of interaction between the photosensitizer, light and oxygen. Vascular-targeted photodynamic therapy (VTP) with padeliporfin may allow tumor-site specific cytotoxicity while sparing adjacent normal tissues.;

UNII : EEO29FZT86;

InChIKey : MZRDSGWDVDESRC-VNWQTDIGSA-L;

CAS number : 759457-82-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 759457-82-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : WST11;

Chemical formula : C37H43N5O9S.Pd;

Details

Origin ID

C78481;

UMLS CUI

C2698706;

Currated CISMeF NLP mapping
- Padeliporfin [ICD-11 Extension code]
- padeliporfin [MeSH Supplementary Concept]
- padeliporfin [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- padeliporfin [ATC Code]
- padeliporfin [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- padeliporfin [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients