Preferred Label : Alogliptin Benzoate;
NCIt synonyms : Benzonitrile, 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-
pyrimidinyl]methyl]-, Monobenzoate;
NCIt definition : The benzoate salt form of alogliptin, a selective, orally bioavailable, pyrimidinedione-based
inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. In addition
to its effect on glucose levels, alogliptin may inhibit inflammatory responses by
preventing the toll-like receptor 4 (TLR-4)-mediated formation of proinflammatory
cytokines.;
UNII : EEN99869SC;
InChIKey : KEJICOXJTRHYAK-XFULWGLBSA-N;
CAS number : 850649-62-6;
Molecule name : SYR-322;
Chemical formula : C18H21N5O2.C7H6O2;
Origin ID : C75186;
UMLS CUI : C2698057;
CISMeF manual mappings
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
http://www.has-sante.fr/portail/jcms/c_1774100/fr/vipdomet
2014
false
false
false
France
French
evaluation of the transparency committee
administration, oral
drug combinations
metformin
hypoglycemic agents
Alogliptin Benzoate
metformin and alogliptin
alogliptin
dipeptidyl-peptidase iv inhibitors
incretins
adult
diabetes mellitus, type 2
treatment outcome
insurance, health, reimbursement
drug therapy, combination
piperidines
uracil
uracil
---
http://www.has-sante.fr/portail/jcms/c_1774095/fr/vipidia
2014
false
false
false
France
French
evaluation of the transparency committee
alogliptin
Alogliptin Benzoate
administration, oral
insurance, health, reimbursement
alogliptin
hypoglycemic agents
incretins
dipeptidyl-peptidase iv inhibitors
drug therapy, combination
diabetes mellitus, type 2
adult
treatment outcome
Product containing alogliptin (medicinal product)
Product containing precisely alogliptin benzoate 6.25 milligram/1 each conventional
release oral tablet (clinical drug)
Product containing precisely alogliptin benzoate 12.5 milligram/1 each conventional
release oral tablet (clinical drug)
Product containing precisely alogliptin benzoate 25 milligram/1 each conventional
release oral tablet (clinical drug)
piperidines
uracil
uracil
---
