Alogliptin - CISMeF

Preferred Label : Alogliptin;

NCIt synonyms : Benzonitrile, 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)- pyrimidinyl]methyl]-;

NCIt definition : A selective, orally bioavailable, pyrimidinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. In addition to its effect on glucose levels, alogliptin may inhibit inflammatory responses by preventing the toll-like receptor 4 (TLR-4)-mediated formation of proinflammatory cytokines.;

UNII : JHC049LO86;

InChIKey : ZSBOMTDTBDDKMP-OAHLLOKOSA-N;

CAS number : 850649-61-5;

Chemical formula : C18H21N5O2;

Details

Origin ID

C76906;

UMLS CUI

C1958126;

Automatic exact mappings (from CISMeF team)
- Alogliptin [ICD-11 Extension code]
CISMeF manual mappings
- Alogliptin (substance) [SNOMED CT concept]
Currated CISMeF NLP mapping
- alogliptin [MeSH concept]
- alogliptin [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing alogliptin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Alogliptin (substance) [SNOMED CT concept]
- Product containing alogliptin (medicinal product) [SNOMED CT concept]
- alogliptin [ATC Code]
- alogliptin [MeSH concept]
- alogliptin [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- alogliptin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Alogliptin Benzoate [NCIt concept]
is_free_acid_or_base_form_of
- Alogliptin Benzoate [NCIt concept]

Keyword's position in hierarchy(ies) :

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