Preferred Label : Mycophenolic Acid;
NCIt synonyms : Acide mycophenolique; Acido micofenolico; Acidum mycophenolicum; 4-Hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-, (E)-; 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-,
(E)-; MPA;
NCIt definition : An antineoplastic antibiotic derived from various Penicillium fungal species. Mycophenolic
acid is an active metabolite of the prodrug mycophenolate mofetil. Mycophenolic acid
inhibits inosine monophosphate dehydrogenase (IMPDH), preventing the formation of
guanosine monophosphate and synthesis of lymphocyte DNA that results in inhibition
of lymphocyte proliferation, antibody production, cellular adhesion, and migration
of T and B lymphocytes. Mycophenolic acid also has antibacterial, antifungal, and
antiviral activities. (NCI04);
UNII : HU9DX48N0T;
InChIKey : HPNSFSBZBAHARI-RUDMXATFSA-N;
CAS number : 24280-93-1; 483-60-3;
Drug name : Myfortic;
Molecule name : Lilly-68618; Ly 68618;
Chemical formula : C17H20O6;
NSC code : 129185;
ChEBI ID : CHEBI:168396;
Codes from synonyms : 30198;
Origin ID : C673;
UMLS CUI : C0026933;
False automatic mappings
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- has_salt_form
- has_target
- is_free_acid_or_base_form_of
https://www.rheuma-net.ch/fr/doc/acide-mycophenolique/viewdocument/345
2024
Switzerland
guideline
mycophenolic acid
Mycophenolic Acid
Background Treatment
acid, nos
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