" /> Mycophenolate Sodium - CISMeF





Preferred Label : Mycophenolate Sodium;

NCIt synonyms : Socium Mycophenolate; 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, monosodium salt, (4E)-;

NCIt definition : The sodium salt form of mycophenolic acid (MPA), with immunosuppressing activity. In vivo, the active molecule MPA reversibly inhibits inosine monophosphate dehydrogenase (IMPDH) which is needed for guanine monophosphate synthesis and stops the proliferation of B and T lymphocytes. Relative to other cell types, lypmocytes are highly dependent on salvage and de novo synthesis of guanine nucleotides, thus making these cells prone to MPA cytotoxicity.;

UNII : WX877SQI1G;

InChIKey : DOZYTHNHLLSNIK-JOKMOOFLSA-M;

CAS number : 37415-62-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 37415-62-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : ERL 080; ERL 080A;

Chemical formula : C17H19O6.Na;

NSC code : 116072;

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09/06/2024


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