Cefepime - CISMeF

Preferred Label : Cefepime;

NCIt synonyms : Cefepime Base;

NCIt definition : A semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefepime binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.;

Alternative definition : NCI-GLOSS: A drug used to treat infection. It belongs to the family of drugs called cephalosporin antibiotics.;

UNII : 807PW4VQE3;

InChIKey : HVFLCNVBZFFHBT-ZKDACBOMSA-N;

CAS number : 88040-23-7;

Chemical formula : C19H24N6O5S2;

ChEBI ID : CHEBI:478164;

Codes from synonyms : CDR0000045032;

Details

Origin ID

C65294;

UMLS CUI

C0055003;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Cefepime [MeSH Descriptor]
- Cefepime [LOINC component]
- Cefepime (substance) [SNOMED CT concept]
- Product containing cefepime (medicinal product) [SNOMED CT concept]
- cefepime [ATC Code]
- cefepime [SNOMED Notion]
- cefepime [MeSH concept]
Validated automatic mappings to BTNT
- cefepime [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Cefepime Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Cefepime Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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