Preferred Label : Cefepime;

MeSH definition : A fourth-generation cephalosporin antibacterial agent that is used in the treatment of infections, including those of the abdomen, urinary tract, respiratory tract, and skin. It is effective against PSEUDOMONAS AERUGINOSA and may also be used in the empiric treatment of FEBRILE NEUTROPENIA.;

MeSH synonym : Cefepim;

MeSH hyponym : BMY-28142; BMY28142;

MeSH CAS label : Pyrrolidinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-1-methyl-, hydroxide, inner salt, (6R-(6alpha,7beta(Z)))-;

MeSH Related Number : 88040-23-7 (Cefepime); I8X1O0607P;

UNII : 807PW4VQE3;

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A fourth-generation cephalosporin antibacterial agent that is used in the treatment of infections, including those of the abdomen, urinary tract, respiratory tract, and skin. It is effective against PSEUDOMONAS AERUGINOSA and may also be used in the empiric treatment of FEBRILE NEUTROPENIA.

https://www.has-sante.fr/jcms/p_3605176/fr/exblifep-cefepime/enmetazobactam-lactamines-inhibiteurs-de-lactamase
2025
false
false
false
France
treatment outcome
insurance, health, reimbursement
cefepime, enmetazobactam drug combination
drug combinations
Cefepime
enmetazobactam
anti-bacterial agents
beta-Lactamase Inhibitors
adult
Complicated urinary tract infection
pyelonephritis
Healthcare-Associated Pneumonia
pneumonia, ventilator-associated
enterobacteriaceae infections
Infection caused by carbapenemase-producing Enterobacteriaceae (disorder)
OXA-48 carbapenemase-producing bacteria (organism)
infusions, intravenous
cefepime and beta-lactamase inhibitor
bacteremia
evaluation of the transparency committee

---
https://www.ema.europa.eu/en/medicines/human/EPAR/exblifep
2024
false
false
false
Netherlands
French
English
treatment outcome
treatment outcome
syndication feed
syndication feed
summary of product characteristics
summary of product characteristics
package leaflet
package leaflet
drug evaluation
drug evaluation
drug approval
drug approval
europe
europe
cefepime, enmetazobactam drug combination
cefepime, enmetazobactam drug combination
cefepime, enmetazobactam drug combination
cefepime, enmetazobactam drug combination
enmetazobactam
enmetazobactam
enmetazobactam
enmetazobactam
Cefepime
Cefepime
Cefepime
Cefepime
beta-Lactamase Inhibitors
beta-Lactamase Inhibitors
beta-Lactamase Inhibitors
beta-Lactamase Inhibitors
anti-bacterial agents
anti-bacterial agents
anti-bacterial agents
anti-bacterial agents
adult
adult
pyelonephritis
pyelonephritis
urinary tract infections
urinary tract infections
Healthcare-Associated Pneumonia
Healthcare-Associated Pneumonia
pneumonia, ventilator-associated
pneumonia, ventilator-associated
bacteremia
bacteremia
infusions, intravenous
infusions, intravenous
product surveillance, postmarketing
product surveillance, postmarketing
drug interactions
drug interactions
pregnancy
pregnancy
breast feeding
breast feeding
cefepime and beta-lactamase inhibitor
cefepime and beta-lactamase inhibitor
drug evaluation, preclinical
drug evaluation, preclinical
OXA-48 carbapenemase-producing bacteria (organism)
OXA-48 carbapenemase-producing bacteria (organism)
Infection caused by carbapenemase-producing Enterobacteriaceae (disorder)
Infection caused by carbapenemase-producing Enterobacteriaceae (disorder)

---
https://www.srlf.org/article/tazocilline-cefepime-reanimation-qui-fait-mieux
2024
France
critical appraisal or critical reading
critical appraisal or critical reading
Cefepime
Cefepime
Device Properties Domain
Device Properties Domain
Reasoning
Reasoning
What Month is it Question
What Month is it Question
Dong Chinese
Dong Chinese
Resuscitation
Resuscitation
Cefepime
Cefepime
Foundation for the Accreditation of Cellular Therapy
Foundation for the Accreditation of Cellular Therapy
Doctor of Osteopathic Medicine
Doctor of Osteopathic Medicine
Better than Others
Better than Others
cefepime
cefepime
resuscitation
resuscitation
Improved
Improved
Dominican Republic
Dominican Republic

---
https://www.has-sante.fr/portail/jcms/c_2884368/fr/cefepime-noridem
2018
false
false
false
France
drugs, generic
drugs, generic
evaluation of the transparency committee
evaluation of the transparency committee
cefepime
cefepime
cephalosporins
cephalosporins
Cefepime
Cefepime

---
https://www.has-sante.fr/portail/jcms/c_2847902/fr/cefepime-gerda
2018
false
false
false
France
French
evaluation of the transparency committee
cefepime
cephalosporins
Cefepime

---
https://ansm.sante.fr/informations-de-securite/cefepime-axepim-r-et-ses-generiques-rappel-des-risques-deffets-indesirables-neurologiques-graves-lors-du-non-respect-des-posologies-recommandees-notamment-en-cas-dinsuffisance-renale
2018
false
false
false
France
French
guidelines for drug use
pharmacovigilance note
renal insufficiency
anti-bacterial agents
anti-bacterial agents
cefepime
Chemically Induced Neurotoxicity
nervous system diseases
aged
child
adult
injections
Cefepime
Cefepime

---
http://www.has-sante.fr/portail/jcms/c_1334811/axepim
http://www.has-sante.fr/portail/jcms/c_1334810/axepim-17102012-avis-ct11758
http://www.has-sante.fr/portail/jcms/c_645036/axepim-sortie-de-la-reserve-hospitaliere-decret-2004
http://www.has-sante.fr/portail/jcms/c_400896/axepim
http://www.has-sante.fr/portail/display.jsp?id=c_399723
2012
false
France
French
antibiotic therapy
adult
infant
child
anti-bacterial agents
Infections
cefepime
neutropenia
fever
urinary tract infections
respiratory tract infections
community-acquired infections
biliary tract diseases
pneumonia, bacterial
bacteremia
sepsis
septicemia
evaluation of the transparency committee
guidelines for drug use
Cefepime

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68804495
2012
France
summary of product characteristics
package leaflet
powders
injections
Cefepime

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65002725
2012
France
summary of product characteristics
package leaflet
injections
powders
Cefepime

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60615311
2012
France
summary of product characteristics
summary of product characteristics
package leaflet
package leaflet
powders
powders
injections
injections
Cefepime
Cefepime

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65108212
2012
France
summary of product characteristics
package leaflet
injections
powders
Cefepime

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62673427
2012
France
summary of product characteristics
summary of product characteristics
package leaflet
package leaflet
injections
injections
powders
powders
Cefepime
Cefepime

---
https://www.lecrat.fr/?s=C%C3%A9f%C3%A9pime
2009
false
France
French
antibiotic therapy
antibiotic therapy
pregnancy
pregnancy
anti-bacterial agents
anti-bacterial agents
cefepime
cefepime
drug information
drug information
Cefepime
Cefepime

---
http://www.meddispar.fr/medicaments/3702300
2008
France
French
cephalosporins
cephalosporins
pharmaceutical solutions
pharmaceutical solutions
drug prescriptions
drug prescriptions
legislation, drug
legislation, drug
injections
injections
cefepime
cefepime
drug information
drug information
Cefepime
Cefepime

---
http://www.meddispar.fr/medicaments/3702346
2008
France
French
cephalosporins
pharmaceutical solutions
drug prescriptions
legislation, drug
injections
cefepime
drug information
Cefepime

---
http://www.meddispar.fr/medicaments/3702292
2008
France
French
drug prescriptions
drug prescriptions
legislation, drug
legislation, drug
injections
injections
cephalosporins
cephalosporins
cefepime
cefepime
drug information
drug information
Cefepime
Cefepime

---
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24/08/2025


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