NCIt definition : A synthetic levoisomer of thyroxine (T4), similar to the endogenous hormone produced
by the thyroid gland. Thyroxine is de-iodinated to form triiodothyronine (T3) in the
peripheral tissues. T3 enters the cell and binds to nuclear thyroid hormone receptors,
and the hormone-receptor complex in turn triggers gene expression and produces proteins
required in the regulation of cellular respiration, thermogenesis, cellular growth
and differentiation, and metabolism of proteins, carbohydrates and lipids. T4 and
T3 also possess cardiac stimulatory effect.;
https://www.srlf.org/article/levothyroxine-don-dorgane-cest-mort 2024 France critical appraisal or critical reading Organ Transplantation Dead Clinical Status Ordinal Scale Outcome 7 Levothyroxine Adverse Event Associated with Death Death Domain Death Indicator death death, nos death thyroxine organ part organ donation Levothyroxine tissue and organ procurement