NCIt related terms : Sodium levothyroxine; Thyroid hormone replacement;
NCIt definition : The sodium salt of levothyroxine, a synthetic levoisomer of thyroxine (T4) that is
similar to the endogenous hormone produced by the thyroid gland. In peripheral tissues,
levothyroxine is deiodinated by 5'-deiodinase to form triiodothyronine (T3). T3 enters
the cell and binds to nuclear thyroid hormone receptors; the activated hormone-receptor
complex in turn triggers gene expression and produces proteins required in the regulation
of cellular respiration; thermogenesis; cellular growth and differentiation; and the
metabolism of proteins, carbohydrates and lipids. T3 also exhibits cardiostimulatory
effects.;
UNII : 9J765S329G;
InChIKey : JMHCCAYJTTWMCX-QWPJCUCISA-M;
CAS number : 25416-65-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 25416-65-3
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;