thyroxine - CISMeF

Preferred Label : thyroxine;

MeSH definition : The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.;

MeSH synonym : thyroid hormone, t4; thyroxin; o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine; t4 thyroid hormone; 3,5,3',5'-tetraiodothyronine;

CISMeF synonym : aventis brand of levothyroxine sodium; forest brand of levothyroxine sodium; monarch brand of levothyroxine sodium; merck lipha santé brand of levothyroxine sodium; genpharm brand of levothyroxine sodium; sigma brand of levothyroxine sodium; abbot brand of levothyroxine sodium; vortex brand of levothyroxine sodium; nourypharma brand of levothyroxine sodium; rudefsa brand of levothyroxine sodium; byk brand of levothyroxine sodium; watson brand of levothyroxine sodium; Berlin-Chemie brand of levothyroxine sodium; berlin chemie brand of levothyroxine sodium; kern brand of levothyroxine sodium; hexal brand 1 of levothyroxine sodium; GlaxoSmithKline brand of levothyroxine sodium; goldshield brand of levothyroxine sodium; allphar brand of levothyroxine sodium; GlaxoWellcome brand of levothyroxine sodium; merck brand of levothyroxine sodium; hexal brand 2 of levothyroxine sodium; betapharm brand of levothyroxine sodium; sanofi synthelabo brand of levothyroxine sodium; henning berlin brand of levothyroxine sodium; roche brand of levothyroxine sodium; mova brand of levothyroxine sodium; delalande brand of levothyroxine sodium; LThyroxin beta; LThyroxin henning; LevoT; deladande, levothyroxin; delalande, levothyroxin; leo, tiroxina; levothyroxine;

DeCS synonym : L vothyrox;

MeSH hyponym : eltroxin; tiroidine; levoxyl; levothyroid; novothyrox; L-Thyroxin beta; synthroid; synthrox; thyrax; levoxine; levothyroxine sodium; eltroxine; L-Thyrox; dexnon; lévothyrox; tiroxina leo; eferox; levothyroxin deladande; L-Thyroxin henning; euthyrox; Levo-T; unithroid; levothroid; L-Thyroxine roche; berlthyrox; oroxine; novothyral; Sodium Levothyroxine; Thevier; Eutirox; L Thyrox; L Thyroxin beta; L Thyroxin Henning; O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine; L-Thyroxine; L Thyroxine; L-3,5,3',5'-Tetraiodothyronine; L Thyroxine Roche; Levo T; Levothyroxin Delalande;

MeSH CAS label : tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-;

MeSH Related Number : 7488-70-2 (Thyroxine); 51-48-9;

Registry Number MeSH : 7488-70-2;

MeSH annotation : /blood: consider also HYPERTHYROXINEMIA;

Wikipedia link : https://en.wikipedia.org/wiki/Thyroxine;

Is substance : O;

UNII : Q51BO43MG4;

InChIKey : XUIIKFGFIJCVMT-LBPRGKRZSA-N;

Details

Origin ID

D013974;

UMLS CUI

C0040165;

ATC code(s)
- combinations of levothyroxine and liothyronine [ATC Code]
- levothyroxine sodium [ATC Code]
- levothyroxine sodium and iodine compounds [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Thyroxine [ICD-11 Extension code]
- Thyroxine [MedDRA Preferred Term]
- Thyroxine [NCIt concept]
- Thyroxine [LOINC component]
- Thyroxine (substance) [SNOMED CT concept]
- thyroxine [SNOMED Notion]
False automatic mappings
- dextrothyroxine [Substance BNPC]
Record concept(s)
- L-Thyrox [MeSH concept]
- L-Thyroxin beta [MeSH concept]
- L-Thyroxin henning [MeSH concept]
- L-Thyroxine roche [MeSH concept]
- Levo-T [MeSH concept]
- Levothyroxine [MeSH concept]
- berlthyrox [MeSH concept]
- dexnon [MeSH concept]
- eferox [MeSH concept]
- eltroxin [MeSH concept]
- eltroxine [MeSH concept]
- euthyrox [MeSH concept]
- levothroid [MeSH concept]
- levothyroid [MeSH concept]
- levothyroxin deladande [MeSH concept]
- levothyroxine sodium [MeSH concept]
- levoxine [MeSH concept]
- levoxyl [MeSH concept]
- lévothyrox [MeSH concept]
- novothyral [MeSH concept]
- novothyrox [MeSH concept]
- oroxine [MeSH concept]
- synthroid [MeSH concept]
- synthrox [MeSH concept]
- thyrax [MeSH concept]
- thyroxine [MeSH concept]
- tiroidine [MeSH concept]
- tiroxina leo [MeSH concept]
- unithroid [MeSH concept]
Related MeSH Supplementary Concept(s)
- 3,3',5,5'-tetraiodothyroformic acid [MeSH Supplementary Concept]
- 3,5,3',5'-tetraiodothyropropionic acid [MeSH Supplementary Concept]
- 3-maleimidobenzoylthyroxine methyl ester [MeSH Supplementary Concept]
- N-bromoacetylthyroxine [MeSH Supplementary Concept]
- etiroxate [MeSH Supplementary Concept]
- nano-diamino-tetrac [MeSH Supplementary Concept]
- tetraiodothyroacetic acid [MeSH Supplementary Concept]
- thyroxamine [MeSH Supplementary Concept]
- thyroxine glucuronide [MeSH Supplementary Concept]
- thyroxine sulfate [MeSH Supplementary Concept]
- thyroxine, triiodothyronine drug combination [MeSH Supplementary Concept]
See also
- hyperthyroxinemia [MeSH Descriptor]
- receptors, thyroid hormone [MeSH Descriptor]
See also (suggested by CISMeF)
- thyroxine-binding proteins [MeSH Descriptor]
See also inter- (CISMeF)
- Levothyroxine [NCIt concept]
- Levothyroxine [ICD-11 Extension code]
- Levothyroxine Sodium [International Nonproprietary Name]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Levothyroxine [LOINC Challenge]
- Levothyroxine [LOINC component]
- Levothyroxine (substance) [SNOMED CT concept]
- Product containing levothyroxine (medicinal product) [SNOMED CT concept]
- Product containing thyroxine (medicinal product) [SNOMED CT concept]
- Thyroxine [LOINC part]
- Thyroxine [LOINC component]
- Thyroxine [NCIt concept]
- Thyroxine (substance) [SNOMED CT concept]
- tetraiodothyronine preparation [SNOMED Notion]
- thyroxine [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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