" /> Pemetrexed - CISMeF





Preferred Label : Pemetrexed;

NCIt synonyms : Multitargeted Antifolate; L-Glutamic Acid, N-(4-(2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl); MTA; Pemetrexed Base;

NCIt definition : A synthetic pyrimidine-based antifolate. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS), which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis.;

UNII : 04Q9AIZ7NO;

InChIKey : WBXPDJSOTKVWSJ-ZDUSSCGKSA-N;

CAS number : 137281-23-3;

Drug name : Pemfexy;

Chemical formula : C20H21N5O6;

NSC code : 698037;

ChEBI ID : CHEBI:63616;

Codes from synonyms : 395;

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Keyword's position in hierarchy(ies) : arborescence

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08/05/2025


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