RASSF1 wt Allele

Preferred Label : RASSF1 wt Allele;

NCIt synonyms : NORE2A; RASSF1A; REH3P21; RDA32; 123F2; Ras Association Domain Family Member 1 wt Allele; Ras Association (RalGDS/AF-6) Domain Family 1 Gene;

NCIt definition : Human RASSF1 wild-type allele is located in the vicinity of 3p21.3 and is approximately 11 kb in length. This allele, which encodes Ras association domain-containing protein 1, is involved in death receptor-dependent apoptosis. Loss or altered expression of the gene is associated with the pathogenesis of a variety of cancers, including lung cancer.;

GenBank Accession Number : NM_007182;

Details

Origin ID

C60666;

UMLS CUI

C1882525;

OMIM relation
- Ras association domain family protein 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3p21.3 [NCIt concept]
gene_is_element_in_pathway
- Bladder Cancer Pathway [NCIt concept]
- Non-Small Cell Lung Cancer Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Process [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Suppression [NCIt concept]

Keyword's position in hierarchy(ies) :

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