Binetrakin - CISMeF

Preferred Label : Binetrakin;

NCIt synonyms : IL-4; B Cell Proliferating Factor; T-Cell Growth Factor 2; RHIL-4; BCSF 1; BCGF; B-Cell Stimulating Factor; Mast Cell Growth Factor-2; MCGF 2; B-Cell Stimulatory Factor 1; Recombinant Human IL-4; B-Cell Growth Factor; Therapeutic Interleukin-4; Interleukin 4 (Human) 129;

NCIt related terms : Interleukin-4;

NCIt definition : A recombinant agent chemically identical to or similar to the endogenous cytokine interleukin-4 (IL-4). Produced primarily by activated T-cells, IL-4 binds to and activates its cell-surface receptor, stimulating the proliferation and differentiation of activated B-cells and enhancing their ability to present antigens to T-cells. As a potential immunotherapeutic agent, binetrakin also augments the effects of other cytokines on dendritic cells (DC), cytotoxic T lymphocytes (CTL), and tumor-infiltrating lymphocytes (TIL).;

UNII : 751635Z921;

CAS number : 207137-56-2;

Molecule name : SCH 93400;

NSC code : 618085; 620211;

Codes from synonyms : NSC0618085; CDR0000044420;

Details

Origin ID

C589;

UMLS CUI

C3486572;

False automatic mappings
- B-cell growth factor [OMIM Phenotype]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Interleukin 4 [LOINC component]
- Interleukin-4 [FMA entity]
- Interleukin-4 [MeSH Descriptor]
- Interleukin-4 [MeSH concept]
- Interleukin-4 (substance) [SNOMED CT concept]
- interleukin-4 [SNOMED Notion]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_affects_gene_product
- Interleukin-4 Receptor Subunit Alpha [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Cytokine Receptor Activation [NCIt concept]
- Receptor Activation Process [NCIt concept]
chemical_or_drug_has_physiologic_effect
- B-Cell Activation [NCIt concept]
- Immunopotentiation [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Autologous Dendritic Cells/Candida Albicans Skin Test Reagent/CD40-Ligand/gp100 Antigen/Interferon Gamma/Interleukin-4/MART-1 Antigen/Sargramostim/Tyrosinase Peptide [NCIt concept]
- Interleukin-2/Interleukin-4 [NCIt concept]
- Interleukin-2/Interleukin-4/Tumor Infiltrating Lymphocytes [NCIt concept]

Keyword's position in hierarchy(ies) :

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