SMAD7 wt Allele

Preferred Label : SMAD7 wt Allele;

NCIt synonyms : MADH7 Gene; MADH7 wt Allele; MADH8; MADH7; SMAD, Mothers Against DPP Homolog 7 (Drosophila) Gene; Mothers Against Decapentaplegic, Drosophila, Homolog of, 7 Gene; SMAD, Mothers Against DPP Homolog 7 Gene; CRCS3; SMAD Family Member 7 wt Allele; MAD (Mothers Against Decapentaplegic, Drosophila) Homolog 7 Gene; MAD, Mothers Against Decapentaplegic Homolog 7 (Drosophila) Gene;

NCIt definition : Human SMAD7 wild-type allele is located in the vicinity of 18q21.1 and is approximately 31 kb in length. This allele, which encodes mothers against decapentaplegic homolog 7 protein, is involved in the attenuation of tumor growth factor-beta type 1 receptor signal transduction.;

GenBank Accession Number : NM_005904;

Details

Origin ID

C52404;

UMLS CUI

C1705381;

OMIM relation
- Smad family member 7 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 18: 44731079-44700221 [NCIt concept]
gene_in_chromosomal_location
- 18q21.1 [NCIt concept]
gene_is_element_in_pathway
- BMP Receptor Signaling Pathway [NCIt concept]
- HDAC Class I Signaling Pathway [NCIt concept]
- Interferon-Gamma Signaling Pathway [NCIt concept]
- Regulation of Nuclear SMAD2/3 Signaling Pathway [NCIt concept]
- TGF Beta Signaling Pathway BioCarta [NCIt concept]
- TGF-Beta Receptor Signaling Pathway [NCIt concept]
- TGF-beta Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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