Preferred Label : CYP3A4 wt Allele;
NCIt synonyms : CP34; CYP3A3; P450PCN1; CYP3A; CP33; Cytochrome P450, Family IIIA, Member 4 Gene; CYP3; NF-25; P450C3; HLP; CYPIIIA4; P450-PCN1; P450, FAMILY III Gene; Cytochrome P450 Family 3 Subfamily A Member 4 wt Allele; P450-III, Steroid-Inducible Gene; P450-III, Steroid Inducible Gene; Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 Gene;
NCIt definition : Human CYP3A4 wild-type allele is located in the vicinity of 7q21.1 and is approximately
27 kb in length. This allele, which encodes cytochrome P450 3A4 protein, plays a role
in the oxidation of steroids, drugs, carcinogens and other xenobiotics. CYP3A4 gene
dysfunction is associated with both lung cancer and epipodophyllotoxin-induced leukemogenesis.;
GenBank Accession Number : NM_017460;
Origin ID : C52363;
UMLS CUI : C1705261;
OMIM relation
- Semantic type(s)
- concept_is_in_subset
- gene_found_in_organism
- gene_in_chromosomal_location
- gene_is_element_in_pathway
- gene_plays_role_in_process
