NTRK3 wt Allele

Preferred Label : NTRK3 wt Allele;

NCIt synonyms : TRKC; NTRK3; Neurotrophic Tyrosine Kinase, Receptor, Type 3 Gene; Neurotrophic Receptor Tyrosine Kinase 3 wt Allele; Neurotrophic Tyrosine Kinase Receptor 3 Gene;

NCIt definition : Human NTRK3 wild-type allele is located within 15q25 and is approximately 380 kb in length. This allele, which encodes NT-3 growth factor receptor protein, is involved in MAPK signal transduction and cellular differentiation. The allele may also play a role in the development of proprioceptive neurons. Mutations in the gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.;

GenBank Accession Number : NM_002530;

Details

Origin ID

C52201;

UMLS CUI

C1704843;

OMIM relation
- Neurotrophic tyrosine kinase, receptor, type 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 15q25 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Cellular Congenital Mesoblastic Nephroma [NCIt concept]
- Infantile Fibrosarcoma [NCIt concept]
gene_is_element_in_pathway
- Neurotrophin Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Ligand Binding [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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