NCIt related terms : Infantile fibrosarcoma (congenital fibrosarcoma);
NCIt definition : A fibrosarcoma that occurs in infants. It shares identical morphologic features with
adult fibrosarcoma but carries the t(12;15)(p13;q25) translocation that results in
ETV6-NTRK3 gene fusion. It usually affects the superficial and deep soft tissues of
the extremities. The prognosis is generally much more favorable than for adult fibrosarcoma,
and it rarely metastasizes.;
Alternative definition : NICHD: A fibrosarcoma typically congenital, and occurring most commonly within the
first three months of life, sharing identical morphologic features with adult fibrosarcoma
but rarely metastatic. It usually affects the superficial and deep soft tissues of
the extremities. The majority of infantile fibrosarcomas carry the t(12;15)(p13;q25)
translocation.;