Cellular Congenital Mesoblastic Nephroma

Preferred Label : Cellular Congenital Mesoblastic Nephroma;

NCIt synonyms : Childhood Cellular Congenital Mesoblastic Nephroma; Infantile Renal Fibrosarcoma; Cellular Mesoblastic Nephroma;

NCIt definition : A congenital mesoblastic nephroma characterized by increased cellularity, sheet-like proliferation of fibroblastic cells, and increased mitotic activity. Necrotic changes are commonly present.;

Alternative definition : NICHD: A congenital mesoblastic nephroma that is characterized by increased cellularity, sheet-like proliferation of fibroblastic cells, and increased mitotic activity. There is a suggested linkage with infantile fibrosarcoma that is based on both containing the same t(12;15)(p13;q25) translocation, resulting in the ETV6/NTRK3 fusion. This type is associated with risk of recurrence.;

Neoplastic status : Malignant;

Details

Origin ID

C39815;

UMLS CUI

C1320471;

Currated CISMeF NLP mapping
- cellular congenital mesoblastic nephroma [DO Concept]
DO Cross reference
- cellular congenital mesoblastic nephroma [DO Concept]
Disease may have findings
- Necrotic Change [NCIt concept]
Has associated anatomic sites
- Genitourinary System [NCIt concept]
- Kidney [NCIt concept]
- Kidney and Ureter [NCIt concept]
- Urinary System [NCIt concept]
See also inter- (CISMeF)
- Mesoblastic nephroma, cellular (morphologic abnormality) [SNOMED CT concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Mesoblastic nephroma, cellular (morphologic abnormality) [SNOMED CT concept]
- cellular congenital mesoblastic nephroma [DO Concept]
concept_is_in_subset
- NCIt Neoplasm Core Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Hematology-Oncology Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_excludes_normal_tissue_origin
- Germinal Layer [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Fibroblast [NCIt concept]
- Neoplastic Cell [NCIt concept]
disease_has_finding
- Childhood Lesion [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Increased Cellularity Present [NCIt concept]
- Low Grade Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Embryonic Cell [NCIt concept]
disease_has_normal_tissue_origin
- Embryonic Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Kidney [NCIt concept]
disease_mapped_to_gene
- ETV6/NTRK3 Fusion Gene [NCIt concept]
- NTRK3 Gene [NCIt concept]
pathogenesis_of_disease_involves_gene
- ETV6/NTRK3 Fusion Gene [NCIt concept]
- NTRK3 Gene [NCIt concept]
- NTRK3 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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