" /> HMGB1 wt Allele - CISMeF





Preferred Label : HMGB1 wt Allele;

NCIt synonyms : High Mobility Group Protein 1 Gene; Nonhistone Chromosomal Protein HGM1 Gene; Chromosomal Protein, Nonhistone, HMG1 Gene; Amphoterin Gene; SBP-1 Gene; Sulfoglucuronyl Carbohydrate Binding Protein Gene; HMG1 Gene; High-Mobility Group (Nonhistone Chromosomal) Protein 1 Gene; High-Mobility Group Box 1 wt Allele; HMG3 Gene; HMG-1 Gene;

NCIt definition : Human HMGB1 wild-type allele is located within 13q12 and is approximately 159 kb in length. This allele, which encodes high mobility group protein B1, is involved in a number of DNA-related subcellular processes such as initiation of transcription, DNA repair and DNA recombination. Expression of the HMGB1 gene is associated with inflammation resulting in both lethal conditions (e.g., endotoxemia, sepsis) and diseases such as arthritis.;

NCIt note : The HMGB1 gene has been implicated in the activation of human tumor cell migration.;

GenBank Accession Number : NM_002128;

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07/05/2024


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