CCR5 wt Allele

Preferred Label : CCR5 wt Allele;

NCIt synonyms : C-C Chemokine Receptor Type 5 Gene; HIV-1 Fusion Co-Receptor Gene; CD195 Antigen Gene; CKR5; CMKBR5; Chemokine (C-C Motif) Receptor 5 Gene; Chemokine (C-C Motif) Receptor 5 (Gene/Pseudogene) Gene; C-C CKR-5; CHEMR13; CKR-5; CC-CKR-5; C-C Motif Chemokine Receptor 5 (Gene/Pseudogene) Gene; Chemokine, CC Motif, Receptor 5 Gene; IDDM22; CD195; CCCKR5; C-C Motif Chemokine Receptor 5 wt Allele; CCR-5;

NCIt definition : Human CCR5 wild-type allele is located within 3p21 and is approximately 6 kb in length. This allele, which encodes C-C chemokine receptor type 5 protein, plays a role in monocyte chemotaxis and G protein-coupled signal transduction. Defective alleles of this gene are associated with HIV infection resistance.;

GenBank Accession Number : NM_000579;

Details

Origin ID

C51321;

UMLS CUI

C1704797;

Automatic exact mappings (from CISMeF team)
- C-C motif chemokine receptor 5 [ORDO Gene]
- CCR5 gene [LOINC component]
- CMKBR5 gene [LOINC component]
- Chemokine (C-C motif) receptor 5 (gene/pseudogene) [ORDO Gene]
- Chemokine, CC motif, receptor 5 [OMIM gene]
- Type 1 diabetes mellitus 22 [OMIM Phenotype]
- diabetes mellitus, Insulin-Dependent, 22 [MeSH Supplementary Concept]
- receptors, ccr5 [MeSH Descriptor]
- type 1 diabetes mellitus 22 [DO Concept]
OMIM relation
- Chemokine, CC motif, receptor 5 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- HIV Infection [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 6: 46386637-46392695 [NCIt concept]
gene_in_chromosomal_location
- 3p21 [NCIt concept]
gene_is_element_in_pathway
- CCR5 Signaling Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- IL12 Signaling Pathway [NCIt concept]
- NO2-Dependent IL12 Pathway [NCIt concept]
- T-Cell Polarization Pathway [NCIt concept]
gene_plays_role_in_process
- Chemotactic Process [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Immunoregulation [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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