NCIt definition : Human NOS3 wild-type allele is located within 7q36 and is approximately 24 kb in length.
This allele, which encodes nitric-oxide synthase, endothelial protein, is involved
in the biosynthesis of nitric oxide from L-arginine and molecular oxygen. Certain
allelic variants of the NOS3 gene are associated with susceptibility to atherosclerosis,
pregnancy-induced hypertension, pulmonary hypertension or late-onset Alzheimer's disease.;