HDAC3 wt Allele

Preferred Label : HDAC3 wt Allele;

NCIt synonyms : Histone Deacetylase 3 wt Allele; RPD3; RPD3-2; HD3;

NCIt definition : Human HDAC3 wild-type allele is located within 5q31 and is approximately 16 kb in length. This allele, which encodes histone deacetylase 3 protein, plays a role in the both the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4) and the binding of transcription factor YY1. Deregulation of HDAC3 gene expression is associated with colon cancer.;

GenBank Accession Number : NM_003883;

Details

Origin ID

C49391;

UMLS CUI

C1706603;

OMIM relation
- Histone deacetylase 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 5: 140996596-140980627 [NCIt concept]
gene_in_chromosomal_location
- 5q31 [NCIt concept]
gene_is_element_in_pathway
- Chromatin Remodeling Complex and Coactivator Pathway [NCIt concept]
- Estrogen Receptor Regulation by CARM1 Pathway [NCIt concept]
- RELA Pathway [NCIt concept]
gene_plays_role_in_process
- Chromatin Remodeling [NCIt concept]
- Hydrolysis [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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