NCIt definition : An orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic
activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1,
HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress
these receptors. (NCI05);
Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. It belongs
to the family of drugs called protein tyrosine kinase inhibitors.;