Forkhead Box Protein C2

Preferred Label : Forkhead Box Protein C2;

NCIt synonyms : MFH-1 Protein; Transcription Factor FKH-14; Mesenchyme Fork Head Protein 1; Forkhead Box C2; FOXC2;

NCIt definition : Forkhead box protein C2 (501aa, 53 kDa) is encoded by the human FOXC2 gene. This protein is involved in the formation of special mesenchymal tissues, and has been isolated in the nucleus. The protein also plays a role in adipocyte metabolism by increasing the sensitivity of the beta-adrenergic cAMP protein kinase A.;

Details

Origin ID

C48221;

UMLS CUI

C1567684;

Currated CISMeF NLP mapping
- mesenchyme fork head 1 protein [MeSH concept]
- mesenchyme fork head 1 protein [MeSH Supplementary Concept]
OMIM relation
- Forkhead box c2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- FOXC2 protein, human [MeSH concept]
gene_encodes_gene_product
- FOXC2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Forkhead Box [NCIt concept]
gene_product_is_element_in_pathway
- Insulin Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Histogenic Process [NCIt concept]
- Transcription [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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