NCIt definition : The sodium salt form of fondaparinux, a synthetic glucopyranoside with antithrombotic
activity. Fondaparinux sodium selectively binds to antithrombin III, thereby potentiating
the innate neutralization of activated factor X (Factor Xa) by antithrombin. Neutralization
of Factor Xa inhibits its activity and interrupts the blood coagulation cascade, thereby
preventing thrombin formation and thrombus development. (NCI05);
Alternative definition : NCI-GLOSS: A drug used to prevent blood clots from forming inside blood vessels in
the leg. It is being studied in the prevention of blood clots in some cancer patients,
including women having surgery for cancer of the reproductive tract. It is a type
of anticoagulant.;
UNII : X0Q6N9USOZ;
InChIKey : XEKSTYNIJLDDAZ-JASSWCPGSA-D;
CAS number : 114870-03-0;
Drug name : Arixtra;
Chemical formula : C31H43N3O49S8.10Na;
ChEBI ID : CHEBI:31632;
Codes from synonyms : CDR0000546738; CDR0000546739; CDR0000528027;