Fondaparinux Sodium

Preferred Label : Fondaparinux Sodium;

NCIt synonyms : Methyl O-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1- 4)-O-beta-D-glucopyra-nuronosyl-(1- 4)-O-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1- 4)-O-2-O-sulfo-alpha-L-idopyranuronosyl-(1- 4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, decasodium salt;

NCIt related terms : Arixtra; fondaparinux;

NCIt definition : The sodium salt form of fondaparinux, a synthetic glucopyranoside with antithrombotic activity. Fondaparinux sodium selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin. Neutralization of Factor Xa inhibits its activity and interrupts the blood coagulation cascade, thereby preventing thrombin formation and thrombus development. (NCI05);

Alternative definition : NCI-GLOSS: A drug used to prevent blood clots from forming inside blood vessels in the leg. It is being studied in the prevention of blood clots in some cancer patients, including women having surgery for cancer of the reproductive tract. It is a type of anticoagulant.;

UNII : X0Q6N9USOZ;

InChIKey : XEKSTYNIJLDDAZ-JASSWCPGSA-D;

CAS number : 114870-03-0;

Drug name : Arixtra;

Chemical formula : C31H43N3O49S8.10Na;

ChEBI ID : CHEBI:31632;

Codes from synonyms : CDR0000546738; CDR0000546739; CDR0000528027;

Details

Origin ID

C47539;

UMLS CUI

C1099664;

See also inter- (CISMeF)
- Product containing fondaparinux (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Fondaparinux [LOINC component]
- Fondaparinux [MeSH Descriptor]
- Fondaparinux [SMS substance]
- Fondaparinux (substance) [SNOMED CT concept]
- fondaparinux [ATC Code]
- fondaparinux [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_free_acid_or_base_form
- Fondaparinux [NCIt concept]
has_target
- Antithrombin-III [NCIt concept]
is_salt_form_of
- Fondaparinux [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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