Fondaparinux - CISMeF

Preferred Label : Fondaparinux;

NCIt synonyms : Natural Heparin Pentasaccharide;

NCIt definition : A synthetic glucopyranoside with antithrombotic activity. Fondaparinux selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin. Neutralization of Factor Xa inhibits its activity and interrupts the blood coagulation cascade, thereby preventing thrombin formation and thrombus development.;

Alternative definition : NCI-GLOSS: A drug used to prevent blood clots from forming inside blood vessels in the leg. It is being studied in the prevention of blood clots in some cancer patients, including women having surgery for cancer of the reproductive tract. It is a type of anticoagulant.; ACC/AHA: Fondaparinux is a synthetic anticoagulant based on the pentasaccharide sequence that makes up the minimal antithrombin-binding region of heparin.;

UNII : J177FOW5JL;

InChIKey : KANJSNBRCNMZMV-ABRZTLGGSA-N;

CAS number : 104993-28-4;

Molecule name : ORG 31540; SR 90107; PENTA;

Chemical formula : C31H53N3O49S8;

ChEBI ID : CHEBI:61033;

Codes from synonyms : CDR0000528027; 230;

Details

Origin ID

C73142;

UMLS CUI

C1098510;

Automatic exact mappings (from CISMeF team)
- PENTA [MeSH concept]
- PENTA [MeSH Supplementary Concept]
- Pentasomy X [ORDO Disease]
- rubiaceae [MeSH Descriptor]
CISMeF manual mappings
- Fondaparinux (substance) [SNOMED CT concept]
See also inter- (CISMeF)
- Product containing fondaparinux (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Fondaparinux [MeSH Descriptor]
- Fondaparinux [LOINC component]
- Fondaparinux (substance) [SNOMED CT concept]
- Product containing fondaparinux (medicinal product) [SNOMED CT concept]
- fondaparinux [ATC Code]
- fondaparinux [MeSH concept]
Validated automatic mappings to BTNT
- fondaparinux [ATC Code]
concept_is_in_subset
- ACC/AHA COVID-19 Appendix Authorized Values [NCIt concept]
- ACC/AHA Cardiovascular and Noncardiovascular Complications of COVID-19 Terminology [NCIt concept]
- Appendix 8: Pharmacological Therapy Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
- Therapies for Supportive Care During COVID-19 Infection Terminology [NCIt concept]
has_salt_form
- Fondaparinux Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Fondaparinux Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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