Leptin - CISMeF

Preferred Label : Leptin;

NCIt synonyms : Obese Protein; Obesity Factor; LEP;

NCIt definition : Leptin (167 aa, 16 kDa) is encoded by the human LEP gene. This protein is secreted by adipocytes and plays a role in the regulation of both appetite and body fat stores.;

NCI Metathesaurus CUI : CL964107;

Details

Origin ID

C46081;

UMLS CUI

C4742979;

Currated CISMeF NLP mapping
- Leptin [LOINC component]
- leptin [MeSH Descriptor]
- leptin [MeSH concept]
False automatic mappings
- leptin (116-130) [MeSH concept]
- leptin (116-130) [MeSH Supplementary Concept]
OMIM relation
- Leptin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- LEP protein, human [MeSH Supplementary Concept]
- Leptin [LOINC component]
- Leptin (substance) [SNOMED CT concept]
- leptin [MeSH concept]
- leptin [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- LEP Gene [NCIt concept]
- Peptide Hormone Gene [NCIt concept]
gene_product_is_element_in_pathway
- Adipocytokine Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- Insulin Resistance Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Diabetes Mellitus [NCIt concept]
gene_product_plays_role_in_biological_process
- Appetite [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Intermediary Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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