Integrin Inhibition

Preferred Label : Integrin Inhibition;

NCIt definition : Integrin Inhibition involves interference with, or restraint of, the activities of a family of noncovalent heterodimeric transmembrane glycoprotein signal transduction receptors for fibronectin, laminin, and other adhesive extracellular matrix glycoproteins, complement, and other cells. Different alpha and beta complexes vary in ligand-specificity and the intracellular domains interact with cytoskeleton.;

Details

Origin ID

C41585;

UMLS CUI

C1512811;

Semantic type(s)
- Molecular Function [UMLS semantic type]
biological_process_is_part_of_process
- Intercellular Communication Process [NCIt concept]
is_mechanism_of_action_of_chemical_or_drug
- Cilengitide [NCIt concept]
- Integrin Receptor Antagonist GLPG0187 [NCIt concept]
is_physiologic_effect_of_chemical_or_drug
- Etaracizumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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