NCIt definition : A phytopolylphenol pigment isolated from the plant Curcuma longa, commonly known as
turmeric, with a variety of pharmacologic properties. Curcumin blocks the formation
of reactive-oxygen species, possesses anti-inflammatory properties as a result of
inhibition of cyclooxygenases (COX) and other enzymes involved in inflammation; and
disrupts cell signal transduction by various mechanisms including inhibition of protein
kinase C. These effects may play a role in the agent's observed antineoplastic properties,
which include inhibition of tumor cell proliferation and suppression of chemically
induced carcinogenesis and tumor growth in animal models of cancer. (NCI04);
Alternative definition : NCI-GLOSS: A yellow pigment of the spice turmeric that is being studied in cancer
prevention.;
UNII : IT942ZTH98;
InChIKey : VFLDPWHFBUODDF-FCXRPNKRSA-N;
CAS number : 458-37-7;
Molecule name : C.I. 75300;
Chemical formula : C21H20O6;
NSC code : 32982;
ChEBI ID : CHEBI:3962;
Codes from synonyms : 00291; NSC0032982; CDR0000046049;
False automatic mappings