Richter Syndrome

Preferred Label : Richter Syndrome;

NCIt synonyms : Richter's Transformation; Richter's Syndrome; Richter s Syndrome;

NCIt related terms : Richter transformation;

NCIt definition : Transformation of chronic lymphocytic leukemia into aggressive non-Hodgkin lymphoma, usually diffuse large B-cell lymphoma (immunoblastic or centroblastic variant). Occasional cases of transformation to Hodgkin lymphoma have also been described, particularly in patients treated with purine nucleotide analogues. Molecular genetic studies suggest that in approximately half of the cases, the lymphoma is clonally related to the underlying chronic lymphocytic leukemia, whereas in the remaining cases the lymphoma probably represents a secondary, unrelated neoplasm.;

Alternative definition : NCI-GLOSS: A rare condition in which chronic lymphocytic leukemia (CLL) changes into a fast-growing type of lymphoma. Symptoms of Richter syndrome include fever, loss of weight and muscle mass, and other health problems.;

Codes from synonyms : CDR0000489396; CDR0000523286;

Details

Origin ID

C35424;

UMLS CUI

C0349631;

Automatic exact mappings (from CISMeF team)
- Chronic lymphocytic leukemia of B-cell type [ICD-10 Sub-category]
Currated CISMeF NLP mapping
- Richter syndrome [PASCAL descriptor]
- Richter syndrome [Disease (Nov.)]
- Richter syndrome [ICD-11 More detail]
- Richter's syndrome [DO Concept]
- Richter's syndrome [MedDRA Preferred Term]
- Richter's syndrome (disorder) [SNOMED CT concept]
DO Cross reference
- Richter's syndrome [DO Concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Richter syndrome [PASCAL descriptor]
- Richter syndrome [Disease (Nov.)]
- Richter syndrome [ICD-11 More detail]
- Richter's syndrome [MedDRA Preferred Term]
- Richter's syndrome [DO Concept]
- Richter's syndrome (disorder) [SNOMED CT concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_has_associated_disease
- Chronic Lymphocytic Leukemia [NCIt concept]
disease_has_associated_disease
- Recurrent Transformed Chronic Lymphocytic Leukemia [NCIt concept]
- Refractory Transformed Chronic Lymphocytic Leukemia [NCIt concept]
- Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma [NCIt concept]
- Transformed Chronic Lymphocytic Leukemia to Hodgkin Lymphoma [NCIt concept]
- Transformed Small Lymphocytic Lymphoma to Hodgkin Lymphoma [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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