Preferred Label : Tumor Lysis Syndrome;
NCIt definition : A condition of metabolic abnormalities that result from a spontaneous or therapy-related
cytolysis of tumor cells. Tumor lysis syndrome typically occurs in aggressive, rapidly
proliferating lymphoproliferative disorders. Burkitt lymphoma and T cell acute lymphoblastic
leukemia are commonly associated with this syndrome. Metabolic abnormalities include
hyperuricemia, lactic acidosis, hyperkalemia, hyperphosphatemia and hypocalcemia and
may result in renal failure, multiple organ failure, and death.;
Alternative definition : CTCAE: A disorder characterized by metabolic abnormalities that result from a spontaneous
or therapy-related cytolysis of tumor cells.; NCI-GLOSS: A condition that can occur after treatment of a fast-growing cancer, especially
certain leukemias and lymphomas (cancers of the blood). As tumor cells die, they break
apart and release their contents into the blood. This causes a change in certain chemicals
in the blood, which may cause damage to organs, including the kidneys, heart, and
liver.; NICHD: Multiple metabolic abnormalities resulting from tumor cell cytolysis characterized
typically by hyperkalemia, hyperphosphatemia, hyperuricemia, and impaired renal function.;
Codes from synonyms : CDR0000626342; E12365;
Origin ID : C3425;
UMLS CUI : C0041364;
Currated CISMeF NLP mapping
- False automatic mappings
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- may_be_associated_disease_of_disease
