Preferred Label : Burkitt Lymphoma;
NCIt synonyms : Small Non-Cleaved Cell Lymphoma, Burkitt's Type; Burkitt's Lymphoma; Burkitt s Lymphoma;
NCIt related terms : NHL, Burkitt lymphoma (BL); Burkitt lymphoma, unspecified site;
NCIt definition : A highly aggressive lymphoma composed of monomorphic medium-sized B-cells with basophilic
cytoplasm and numerous mitotic figures. It is often associated with the presence of
Epstein-Barr virus (EBV) and is commonly seen in AIDS patients. Three morphologic
variants are recognized: classical Burkitt lymphoma, Burkitt lymphoma with plasmacytoid
differentiation, and atypical Burkitt/Burkitt-like lymphoma. All cases express the
MYC translocation [t(8;14)]. (WHO, 2001);
Alternative definition : NCI-GLOSS: An aggressive (fast-growing) type of B-cell non-Hodgkin lymphoma that occurs
most often in children and young adults. The disease may affect the jaw, central nervous
system, bowel, kidneys, ovaries, or other organs. There are three main types of Burkitt
lymphoma (sporadic, endemic, and immunodeficiency related). Sporadic Burkitt lymphoma
occurs throughout the world, and endemic Burkitt lymphoma occurs in Africa. Immunodeficiency-related
Burkitt lymphoma is most often seen in AIDS patients.;
Neoplastic status : Malignant;
ICD-O code : 9687/3;
Codes from synonyms : CDR0000045203; C83.70;
Origin ID : C2912;
UMLS CUI : C0006413;
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- DO Cross reference
- Disease excludes abnormal cell
- Disease excludes normal cell origin
- Disease may have findings
- False automatic mappings
- Has associated anatomic sites
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_associated_gene
- disease_has_finding
- disease_has_molecular_abnormality
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_mapped_to_gene
- disease_may_have_associated_disease
- disease_may_have_cytogenetic_abnormality
- pathogenesis_of_disease_involves_gene