Classical Burkitt Lymphoma

Preferred Label : Classical Burkitt Lymphoma;

NCIt synonyms : Classical Burkitt's Lymphoma; Classical Burkitt s Lymphoma;

NCIt definition : A Burkitt lymphoma characterized by the presence of a uniform malignant lymphocytic infiltrate that is composed of medium-sized cells with round nuclei and multiple basophilic nucleoli, abundant mitotic figures, and a starry-sky pattern due to the presence of multiple tangible body macrophages.;

Neoplastic status : Malignant;

Details

Origin ID

C7188;

UMLS CUI

C1333063;

Currated CISMeF NLP mapping
- Classic Hodgkin lymphoma [ORDO Disease]
Disease excludes abnormal cell
- Lymphocyte Predominant Cell [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- Bulky Disease [NCIt concept]
- Lymphadenopathy [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
Validated automatic mappings to NTBT
- Classical Hodgkin lymphoma [MedDRA LLT]
- Classical Hodgkin lymphoma [ICD-11 Subcategory]
- Classical Hodgkin lymphoma (disorder) [SNOMED CT concept]
concept_is_in_subset
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic Medium-Sized B-Lymphocyte with Basophilic Cytoplasm [NCIt concept]
disease_has_finding
- High Mitotic Activity [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Starry Sky Pattern [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]
- MYC Gene Amplification [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Germinal Center B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_mapped_to_gene
- MYC Gene [NCIt concept]
disease_may_have_associated_disease
- Tumor Lysis Syndrome [NCIt concept]
disease_may_have_cytogenetic_abnormality
- t(2;8)(p11;q24) [NCIt concept]
- t(8;14)(q24;q32) [NCIt concept]
- t(8;22)(q24;q11) [NCIt concept]

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