" /> Classical Hodgkin lymphoma - CISMeF





ICD-11 code : 2B30.1;

Preferred Label : Classical Hodgkin lymphoma;

ICD-11 definition : Classical Hodgkin lymphoma is a B-cell lymphoma characterized histologically by the presence of large mononuclear Hodgkin cells and multinucleated Reed-Sternberg (HRS) cells. A monoclonal B-cell lymphoproliferation in the vast majority of cases. It is characterized by a bimodal age distribution (15-30 years of life and late life) and is often associated with EBV infection. In less than 5% of cases it is a monoclonal proliferation of T-lymphocytes. Morphologically, it is characterized by the presence of Reed-Sternberg cells and mononuclear Hodgkin cells. The Reed-Sternberg and mononuclear Hodgkin cells are CD30 positive in nearly all cases and CD15 positive in the majority of cases.;

ICD-11 inclusion : Hodgkin paragranuloma, nodular; Hodgkin granuloma; Classical Hodgkin lymphoma, type not specified; Hodgkin sarcoma; Hodgkin paragranuloma;

ICD-11 "unspecified" category code : 2B30.1Z;

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Classical Hodgkin lymphoma is a B-cell lymphoma characterized histologically by the presence of large mononuclear Hodgkin cells and multinucleated Reed-Sternberg (HRS) cells. A monoclonal B-cell lymphoproliferation in the vast majority of cases. It is characterized by a bimodal age distribution (15-30 years of life and late life) and is often associated with EBV infection. In less than 5% of cases it is a monoclonal proliferation of T-lymphocytes. Morphologically, it is characterized by the presence of Reed-Sternberg cells and mononuclear Hodgkin cells. The Reed-Sternberg and mononuclear Hodgkin cells are CD30 positive in nearly all cases and CD15 positive in the majority of cases.

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08/05/2025


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