Transcription Factor E2-Alpha

Preferred Label : Transcription Factor E2-Alpha;

NCIt synonyms : Immunoglobulin Transcription Factor 1; Kappa-E2-Binding Factor; ITF1; Transcription Factor-3; TCF3; E2A Immunoglobulin Enhancer Binding Factor E47; E2A Immunoglobulin Enhancer Binding Factor E12; E2A; bHLHb21; Transcription Factor ITF-1; Class B Basic Helix-Loop-Helix Protein 21; TCF-3; Immunoglobulin Enhancer-Binding Factor E12/E47; Transcription Factor 3;

NCIt definition : Transcription factor E2-alpha (654 aa, 68 kDa) is encoded by the human TCF3 gene. This protein plays a role in transcriptional regulation, cell cycle progression and cell lineage commitment.;

Details

Origin ID

C30079;

UMLS CUI

C0914163;

Currated CISMeF NLP mapping
- transcription factor 3 [MeSH Descriptor]
- transcription factor 3 [MeSH concept]
OMIM relation
- Transcription factor 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TCF3 protein, human [MeSH concept]
- TCF3 protein, human [MeSH Supplementary Concept]
- transcription factor 3 [MeSH Descriptor]
- transcription factor 3 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- TCF3 Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- BHLH Protein [NCIt concept]
- DNA Binding Protein [NCIt concept]
gene_product_is_element_in_pathway
- Regulation of Nuclear SMAD2/3 Signaling Pathway [NCIt concept]
- p38 MAPK/MAPKAP Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Fate Control [NCIt concept]
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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