TATA Box-Binding Protein-Like Protein 1

Preferred Label : TATA Box-Binding Protein-Like Protein 1;

NCIt synonyms : TBP-Like Protein 1; TBP-Like Factor; TATA Box-Binding Protein-Related Factor 2; TATA Box Binding Protein-Related Factor 2; TBP-Related Factor 2; TATA Box Binding Protein-Like Protein 1; STUD; TBP-Related Protein; STUD Protein; Second TBP of Unique DNA Protein; 21-kDa TBP-Like Protein; TBP-Like Protein-1; TBPL1;

NCIt definition : TATA box binding protein-like protein 1 (186 aa, 21 kDa) is encoded by the human TBPL1 gene. This protein plays a role in the initiation of transcription from promoters that are not recognized by the transcription factor IID complex.;

NCIt note : TBP-Like Protein 1 substitutes for TBP at some promoters not recognized by TFIID. TBPL1 binds TFIIA and TFIIB, does not bind the TATA box, may be important in expression of some developmentally regulated genes and is essential for spermatogenesis.;

Details

Origin ID

C30078;

UMLS CUI

C1336592;

OMIM relation
- Tata box-binding protein-like protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Basal Transcription Factor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- TBPL1 Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcription Initiation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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