Transcription Initiation Factor TFIID Subunit 5

Preferred Label : Transcription Initiation Factor TFIID Subunit 5;

NCIt synonyms : TAFII-100; TATA Box Binding Protein-Associated Factor RNA Polymerase II D 100kD; TAF5 RNA Polymerase II; TBP-Associated Factor 100kDa; TBP-Associated Factor 2D; TAF(II)100; TAF2D; TATA Box Binding Protein-Associated Factor 100kDa; TBP-Associated Factor 5; TAFII100; Transcription Initiation Factor TFIID 100 kD Subunit; TAF5; TBP-Associated Factor RNA Polymerase II D 100kD; TBP-Associated Factor-5;

NCIt definition : Transcription initiation factor TFIID subunit 5 (800 aa, 87 kDa) is encoded by the human TAF5 gene. This protein plays a role in the assembly of the basal transcription apparatus.;

NCIt note : TBP-Associated Factor 5 interacts strongly with (histone H4-related) TAFII80 and (histone H3-related) TAFII31, as well as with TBP, TAFII250, TAFII28, and TAFII20. A component of the TFTC-HAT complex, TAFII100 contains 1 LisH domain and 6 WD repeats; distinct TAFII100 domains are required for interaction with TFIIFB and for incorporation into TFIID.;

Details

Origin ID

C30066;

UMLS CUI

C0391783;

OMIM relation
- Taf5 rna polymerase II, tata box-binding protein-associated factor, 100-kd [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TAF5 protein, human [MeSH Supplementary Concept]
- TAF5 protein, human [MeSH concept]
gene_encodes_gene_product
- Basal Transcription Factor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- TAF5 Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_is_physical_part_of
- TFIID [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcription Initiation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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