Transcription Initiation Factor TFIID Subunit 4

Preferred Label : Transcription Initiation Factor TFIID Subunit 4;

NCIt synonyms : TAF2C1; TAF4; Transcription Initiation Factor TFIID 135 kDa Subunit; Transcription Initiation Factor TFIID 130 kDa Subunit; TAFII-130; TBP-Associated Factor RNA Polymerase II C1 130kD; TAF(II)135; TAFII130; TAF4A; TATA Box Binding Protein-Associated Factor 135 kD; TAF2C; TAFII135; TATA Box Binding Protein-Associated Factor RNA Polymerase II C1 130kD; TAF4 RNA Polymerase II; RNA Polymerase II TBP-Associated Factor Subunit C; TBP-Associated Factor 4; TBP-Associated Factor 135 kD; TAFII-135; TAF(II)130; TBP-Associated Factor-4;

NCIt definition : Transcription initiation factor TFIID subunit 4 (1085 aa, 110 kDa) is encoded by the human TAF4 gene. This protein is involved in the modulation of transcription.;

NCIt note : TBP-Associated Factor 4, containing 1 TAFH/NHR1 domain, is one of the larger subunits of the multimeric TFIID complex that mediates promoter responses to various activators and repressors. A component of the TFTC-HAT complex, TAF4 interacts with transcription factor CREB and other proteins containing glutamine-rich regions and potentiates transcriptional activation by the AF-2S of the RAR, THR and vitamin D3 receptor.;

Details

Origin ID

C30065;

UMLS CUI

C1336585;

OMIM relation
- Taf4 rna polymerase II, tata box-binding protein-associated factor, 135-kd [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Basal Transcription Factor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- TAF4 Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_is_physical_part_of
- TFIID [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcription Initiation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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