Transcription Initiation Factor TFIID Subunit 2

Preferred Label : Transcription Initiation Factor TFIID Subunit 2;

NCIt synonyms : TAF2; Cofactor of Initiator Function, 150-kD Subunit; TBP-Associated Factor 2; Transcription Initiation Factor TFIID 150 kDa Subunit; TAFII150; TAF2B; TBP-Associated Factor RNA Polymerase II B 150kD; TBP-Associated Factor 150kDa; TATA Box Binding Protein-Associated Factor RNA Polymerase II B 150kD; TAF2 RNA Polymerase II; TAFII-150; RNA Polymerase II TBP-Associated Factor Subunit B; TATA Box Binding Protein-Associated Factor 150kDa; TAF(II)150; TBP-Associated Factor-2; 150 kDa Cofactor of Initiator Function; Cofactor of Initiator Function, 150kD Subunit;

NCIt definition : Transcription initiation factor TFIID subunit 2 (1199 aa, 136 kDa) is encoded by the human TAF2 gene. This protein plays a role in the initiation of transcription.;

NCIt note : TBP-Associated Factor 2 is one of the larger subunits associated with TFIID, shares 53% identity with its Drosophila homologue, and contains a stretch of 7 His residues near the C terminus. Stably associated with TAF2C1, TAF2D, and TBP as an essential cofactor for TFIID/TBP-dependent transcription from promoters containing initiator elements, TAF2B contributes to interactions that determine response of the complex to activators.;

Details

Origin ID

C30063;

UMLS CUI

C0669417;

OMIM relation
- Taf2 rna polymerase II, tata box-binding protein-associated factor, 150-kd [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TAF2 protein, human [MeSH Supplementary Concept]
- TAF2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Basal Transcription Factor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- TAF2 Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_is_physical_part_of
- TFIID [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcription Initiation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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