Transcription Initiation Factor IIE Subunit Beta

Preferred Label : Transcription Initiation Factor IIE Subunit Beta;

NCIt synonyms : GTF2E2; General Transcription Factor IIE Subunit 2; Transcription Initiation Factor IIE Beta Subunit; TFIIE-Beta; General Transcription Factor IIE2 Beta 34kDa; Transcription Initiation Factor-IIE Beta Subunit;

NCIt definition : Transcription initiation factor IIE subunit beta (291 aa, 33 kDa) is encoded by the human GTF2E2 gene. This protein is involved in the mediation of both transcriptional initiation and RNA elongation.;

NCIt note : GTF2E1 appears required with GTF2E2 for stable formation of a preinitiation complex and for basal, as well as Sp1-activated, transcription.;

Details

Origin ID

C29686;

UMLS CUI

C0378730;

Currated CISMeF NLP mapping
- TFIIE beta [MeSH concept]
OMIM relation
- General transcription factor iie, polypeptide 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TFIIE beta [MeSH concept]
gene_encodes_gene_product
- Basal Transcription Factor Gene [NCIt concept]
- GTF2E2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcription Initiation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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